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SAH-EZH2

CAT: 0013-GTR19029119Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19029119Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This small molecule inhibitor disrupts the EZH2/EPP interaction with a Kd of 320 nM, leading to reduced EZH2 expression and H3K27me3 by the PRC2 complex. It halts proliferation and promotes monocyte-to-macrophage differentiation in MLL-AF9 leukemia models, supporting research into epigenetic therapies for hematological cancers.
Field of Research
Epigenetics & Chromatin, Metabolism Research; Epigenetics & Chromatin
Molecular Weight
3432.05
Storage Conditions
-20°C
Notes
For research use only.

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