Recombinant Human Interleukin-2/IL-2 Protein (Mutant)
CAT:
763-PKSH033625-01
Size:
50 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Recombinant Human Interleukin-2/IL-2 Protein (Mutant)
- Background: Interleukin-2(IL-2) is an interleukin; a type of cytokine signaling molecule in the immune system;belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells; NK cells; lymphokine-activated killer cells; monocytes; macrophages and oligodendrocytes. New research has shown that IL-2 mutant reduced toxicity while being more potent at stimulating anti-tumor effector immune cells.
- Abbreviation: Interleukin-2;IL-2
- Synonyms: IL2, IL-2, TCGF, lymphokine, IL3, IL4, IL5, IL6, Aldesleukin, IL-2lymphokine, interleukin-2, Proleukin, interleukin 2, involved in regulation of T-cell clonal expansion, T cell growth factor, T-cell growth factor, IL 2, IL2, Interleukin 2, interleukin2, Involved in regulation of T cell clonal expansion, Lymphokine, POIL2, T Cell Growth Factor, TCGF
- CAS Number: 9000-83-3
- UniProt: P60568
- Accession Number: P60568
- Host: HEK293 Cells
- Origin Species: Human
- Tag: C-His
- Sequence: Ala21-Thr153(L100F,R101D,L105V,I106V,I112F)
- Applications: Cell culture
- Field of Research: immunology
- Purity: > 95 % as determined by reducing SDS-PAGE.
- Bioactivity: Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is 151.39 pg/ml.
- Reconstitution: Please refer to the printed manual for detailed information.
- Molecular Weight: 16&18 kDa
- Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
- Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.