PPARG Polyclonal Antibody

• Background:

  This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

• Abbreviation:

  PPARG

• UniProt:

  P37231, P37238, O88275

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant protein corresponding to Mouse PPARγ

• Target:

  CIMT1; GLM1; NR1C3; Nuclear receptor subfamily 1 group C member 3; OTTHUMP00000185032; OTTHUMP00000185036; Peroxisome proliferator activated nuclear receptor gamma variant 1; Peroxisome proliferator activated receptor gamma 1; Peroxisome Proliferator Activated Receptor gamma; Peroxisome proliferator-activated receptor gamma; PPAR gamma; PPAR-gamma; PPARG; PPARG; PPARG1; PPARG2; PPARgamma

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism; Neuroscience; Stem Cells

• Purification:

  Affinity purification

• Concentration:

  0.58 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  58Da

• Observed Molecular Weight:

  50-60kDa

• Citation 01:

  https://www.sciencedirect.com/science/article/pii/S1388198120301694

• Citation 02:

  https://www.sciencedirect.com/science/article/pii/S0898656818301724

• Citation 03:

  https://www.sciencedirect.com/science/article/pii/S1098882317300783

• Citation 04:

  https://www.sciencedirect.com/science/article/pii/S0006291X19316687

• Citation 05:

  https://europepmc.org/article/med/31999897?javascript_support=no

• Isotype:

  IgG