PPAR gamma Polyclonal Antibody

• Background:

  This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.

• Abbreviation:

  PPAR gamma

• UniProt:

  P37231

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  A synthetic peptide of human PPAR gamma

• Target:

  CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARgamma; PPAR gamma; PPARG

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC; IF

• Field of Research:

  Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism; Neuroscience; Stem Cells

• Purification:

  Affinity purification

• Concentration:

  1 mg/mL

• Dilution:

  IHC 1:50-1:200; IF 1:50-1:20

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  21kDa/54kDa/57kDa

• Observed Molecular Weight:

  57KDa

• Isotype:

  IgG