CYCS Polyclonal Antibody

• Background:

  Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.

• Abbreviation:

  CYCS

• UniProt:

  P99999, P62898, P62897

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  KLH conjugated Synthetic peptide corresponding to Mouse Cytochrome c

• Target:

  Cytochrome C; Somatic; CYC; Cytochrome C; THC4; HCS.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC; IF

• Field of Research:

  Cancer; Cell Biology; Cardiovascular; Metabolism; Signal Transduction

• Purification:

  Affinity purification

• Concentration:

  1.5 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:500-1:1000; IF 1:200-1:800

• Buffer:

  PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  12kDa

• Observed Molecular Weight:

  12kDa

• Citation 01:

  https://link.springer.com/article/10.1007/s11696-019-00894-8

• Isotype:

  IgG