BBC3 Polyclonal Antibody

• Background:

  This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.

• Abbreviation:

  BBC3

• UniProt:

  Q96PG8, Q9BXH1

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  A synthetic peptide of human BBC3 (NP_001120713.1) .

• Target:

  BBC3; JFY-1; JFY1; PUMA

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IF

• Purification:

  Affinity purification

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000; IF 1:50-1:100

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  10kDa/14kDa/20kDa/26kDa

• Observed Molecular Weight:

  20kDa

• Isotype:

  IgG