PSCA Polyclonal Antibody

• Background:

  PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.

• Abbreviation:

  PSCA

• UniProt:

  O43653

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthetic peptide of human PSCA

• Target:

  PRO 232; PRO232; Prostate stem cell antigen

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Stem Cells

• Purification:

  Antigen affinity purification

• Concentration:

  0.78 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:20-1:100

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  13 kDa

• Observed Molecular Weight:

  Refer to figures

• Isotype:

  IgG