RITA1 Polyclonal Antibody

• Background :

  Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.

• Abbreviation :

  RITA1

• UniProt :

  Q96K30

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Fusion protein of human RITA1

• Target :

  C12orf52 ; Chromosome 12 open reading frame 52 ; RBPJ interacting and tubulin associated 1; RBPJ interacting and tubulin associated protein 1; RBPJ-interacting and tubulin-associated protein; RITA; RITA

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  IHC

• Field of Research :

  Developmental biology; Neuroscience; Signal transduction; Stem cells

• Purification :

  Antigen affinity purification

• Concentration :

  0.9 mg/mL

• Dilution :

  IHC 1:50-1:200

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype :

  IgG