IFT57 Polyclonal Antibody

CAT: 0763-E-AB-52949-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0763-E-AB-52949-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity) . Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
Abbreviation
IFT57
UniProt
Q9NWB7
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human IFT57
Target
CDNA FLJ10147 fis clone HEMBA1003369; Dermal papilla derived protein 8; Dermal papilla-derived protein 8; DERP 8; DERP8; Esrrbl 1; Esrrbl1; ESRRBL1 protein; Estrogen related receptor beta like 1; Estrogen related receptor beta like protein 1; Estrogen-related receptor beta-like protein 1; FLJ10147; Hip1 Interacting protein; HIP1 interacting protein HIPPI; Hip1 protein interactor; HIP1-interacting protein; HIPPI; Huntingtin interacting protein 1 interacting protein; Huntingtin interacting protein 1 protein interactor; IFT 57; ift57; IFT57; Intraflagellar transport 57 homolog (Chlamydomonas) ; Intraflagellar transport 57 homolog; Intraflagellar transport protein 57 homolog; MHS4R2; Vestrogen related receptor beta like 1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Neuroscience
Purification
Antigen affinity purification
Concentration
1.5 mg/mL
Dilution
IHC 1:50-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

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