ECH1 Polyclonal Antibody

• Background:

  This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.

• Abbreviation:

  ECH1

• UniProt:

  Q13011

• Host:

  Rabbit

• Reactivity:

  Human; Rat

• Immunogen:

  Fusion protein of human ECH1

• Target:

  4) -dienoyl-CoA isomerase;5) -Delta (2; Delta (3 5) Delta (2 4) dienoyl CoA isomerase; Delta (3 5) Delta (2 4) dienoyl CoA isomerase mitochondrial; Delta (3; Delta3 5 delta2 4 dienoyl CoA isomerase; Dienoyl CoA isomerase; ECH 1; Ech1; ECH1; Enoyl Coenzyme A hydratase 1; Enoyl Coenzyme A hydratase 1 peroxisomal; HPXEL; mitochondrial; MS1034; Peroxisomal enoyl CoA hydratase 1; Peroxisomal enoyl coenzyme A hydratase like protein

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cancer; Cardiovascular; Metabolism; Signal transduction; Tags and Cell markers

• Purification:

  Antigen affinity purification

• Concentration:

  0.9 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:50-1:300

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  36 kDa

• Observed Molecular Weight:

  Refer to figures

• Isotype:

  IgG