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NAPRT Polyclonal Antibody

CAT: 0763-E-AB-52878-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-52878-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Nicotinic acid (NA) is a coenzyme in cellular redox reactions, and is an essential component of metabolic pathways in all living cells. NAPRT1 (Nicotinate phosphoribosyltransferase) is essential for increasing cellular NAD levels and, thus, to prevent oxidative stress of cells. NAPRT1 converts Nicotinic acid (NA; niacin) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD) .
Abbreviation
NAPRT
UniProt
Q6XQN6
Host
Rabbit
Reactivity
Human
Immunogen
Fusion protein of human NAPRT
Target
FHA HIT interacting protein; FHA-HIT-interacting protein; FHIP; NAPRT1; NAPRTase; Nicotinate phosphoribosyltransferase; Nicotinate phosphoribosyltransferase domain containing 1; Nicotinate phosphoribosyltransferase domain-containing protein 1; Nicotinic acid phosphoribosyltransferase; PNCB; PP3856
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell Biology; Epigenetics and Nuclear Signaling; Metabolism; Signal Transduction
Purification
Antigen affinity purification
Concentration
0.66 mg/mL
Dilution
IHC 1:50-1:300
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q6XQN6

Nicotinate phosphoribosyltransferase

PNCB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q6XQN6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NAPRT
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
NAPRTase
EC number
6.3.4.21
Processing
—
Secondary accessions
A7BFI3, Q6PJL1, Q6XQN4, Q6XQN5, Q8N5E8, Q9BRG0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cytoplasm

Molecular function

LigaseTransferase

Ligand

MagnesiumManganeseMetal-binding

PTM

Phosphoprotein

Biological process

Pyridine nucleotide biosynthesis

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