FUNDC2 Polyclonal Antibody

• Background:

  FUNDC2 (FUN14 domain-containing protein 2), also known as HCC-3 (cervical cancer proto-oncogene 3 protein), HCBP6 (hepatitis C virus core-binding protein 6) or DC44, is a 189 amino acid protein belonging to the FUN14 family. The gene encoding FUNDC2 maps to human chromosome Xq28. The X and Y chromosomes are the human sex chromosomes. Chromosome X consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.

• Abbreviation:

  FUNDC2

• UniProt:

  Q9BWH2

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Fusion protein of human FUNDC2

• Target:

  Cervical cancer oncogene 3; Cervical cancer proto oncogene 3 protein; DC44; FLJ33773; FUN14 domain containing 2; FUN14 domain containing protein 2; FUNDC 2; HCBP 6; HCBP6; HCC 3; HCC3; Hepatitis C virus core binding protein 6; MGC131676; MGC2495; OTTHUMP00000015441; OTTHUMP00000061459; PD03104

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Epigenetics and Nuclear Signaling; Metabolism; Microbiology; Signal transduction

• Purification:

  Antigen affinity purification

• Concentration:

  1.02 mg/mL

• Dilution:

  IHC 1:50-1:300

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG