GSKIP Polyclonal Antibody

• Background :

  This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.

• Abbreviation :

  GSKIP

• UniProt :

  Q9P0R6

• Host :

  Rabbit

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Fusion protein of human GSKIP

• Target :

  C14ORF129; Chromosome 14 open reading frame 129 ; GSK3-beta interaction protein; GSK3beta interaction protein; GSKIP; GSKIP; MGC4945; UPF0279

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  IHC

• Field of Research :

  Cell Biology

• Purification :

  Antigen affinity purification

• Concentration :

  0.78 mg/mL

• Dilution :

  IHC 1:30-1:150

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype :

  IgG