TLE6 Polyclonal Antibody

• Background:

  This gene encodes a member of the Groucho/ transducin-like Enhancer of split family of transcriptional co-repressors. The encoded protein is a component of the mammalian subcortical maternal complex, which is required for preimplantation development. In mouse, knock out of this gene results in cleavage-stage embryonic arrest resulting from defective cytoplasmic F-actin meshwork formation and asymmetric cell division. In human, an allelic variant in this gene is associated with preimplantation embryonic lethality. Alternative splicing results in multiple transcript variants.

• Abbreviation:

  TLE6

• UniProt:

  Q9H808

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Fusion protein of human TLE6

• Target:

  Transducin Like Enhancer Of Split 6; PREMBL; GRG6

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Purification:

  Antigen affinity purification

• Concentration:

  1.38 mg/mL

• Dilution:

  IHC 1:50-1:200

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG