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TLE6 Polyclonal Antibody

CAT: 0763-E-AB-52751-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-52751-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the Groucho/ transducin-like Enhancer of split family of transcriptional co-repressors. The encoded protein is a component of the mammalian subcortical maternal complex, which is required for preimplantation development. In mouse, knock out of this gene results in cleavage-stage embryonic arrest resulting from defective cytoplasmic F-actin meshwork formation and asymmetric cell division. In human, an allelic variant in this gene is associated with preimplantation embryonic lethality. Alternative splicing results in multiple transcript variants.
Abbreviation
TLE6
UniProt
Q9H808
Host
Rabbit
Reactivity
Human
Immunogen
Fusion protein of human TLE6
Target
Transducin Like Enhancer Of Split 6; PREMBL; GRG6
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Purification
Antigen affinity purification
Concentration
1.38 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q9H808

Transducin-like enhancer protein 6

TLE6_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9H808
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TLE6
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
J3KMZ1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Disease

Disease variant

PTM

Phosphoprotein

Domain

RepeatWD repeat

Biological process

TranscriptionTranscription regulation

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