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ERAL1 Polyclonal Antibody

CAT: 0763-E-AB-52749-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-52749-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a GTPase that localizes to the mitochondrion. The encoded protein binds to the 3' terminal stem loop of 12S mitochondrial rRNA and is required for proper assembly of the 28S small mitochondrial ribosomal subunit. Deletion of this gene has been shown to cause mitochondrial dysfunction, growth retardation, and apoptosis. Several transcript variants encoding different isoforms have been found for this gene.
Abbreviation
ERAL1
UniProt
O75616
Host
Rabbit
Reactivity
Human
Immunogen
Fusion protein of human ERAL1
Target
CEGA; Conserved ERA like GTPase; Conserved ERA-like GTPase; ERA; Era (E.coli G protein homolog) like 1; Era G protein like 1 (E.coli) ; Era G protein like 1; ERA W; ERA-like protein 1; ERA-W; Eral1; ERAL1; ERAL1A; ERAW; GTP binding protein era homolog; GTPase Era; GTPase Era; mitochondrial; GTPase human homolog of E.coli essential cell cycle protein Era; H-ERA; HERA A; hERA; HERA B; HERAA; HERAB; mitochondrial
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Signal Transduction
Purification
Antigen affinity purification
Concentration
1.2 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
48 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

UniProtKB · O75616

GTPase Era, mitochondrial

ERAL1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O75616
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ERAL1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
H-ERA, hERA
EC number
—
Processing
Precursor
Secondary accessions
B3KN21, C9JEC6, O75617, Q8WUY4, Q96LE2, Q96TC0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

DeafnessDisease variant

Ligand

GTP-bindingNucleotide-binding

Cellular component

MembraneMitochondrionMitochondrion inner membrane

PTM

Phosphoprotein

Biological process

Ribosome biogenesis

Molecular function

RNA-bindingrRNA-binding

Domain

Transit peptide

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