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C4BPB Polyclonal Antibody

CAT: 0763-E-AB-52505-01Size: 20 µLDry Ice: NoHazardous: No
CAT#: E-AB-52505-01Size: 20 µL
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.
Abbreviation
C4BPB
UniProt
P20851
Host
Rabbit
Reactivity
Human
Immunogen
Fusion protein of human C4BPB
Target
C4b binding protein beta chain; C4b-binding protein beta chain; C4BP; C4BPB; C4BPB; Complement component 4 binding protein beta; Complement component 4 binding protein beta chain; Complement component 4-binding protein beta; OTTHUMP00000034288; OTTHUMP00000034289; OTTHUMP00000034375; OTTHUMP0000003474; Proline rich protein; PRP
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Immunology
Purification
Antigen affinity purification
Concentration
0.7 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

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