Products for Research Use Only

Α-SMA Polyclonal Antibody

CAT: 0763-E-AB-34268-01Size: 20 µLDry Ice: NoHazardous: No
Product image 1Product image 2
1 / 2
CAT#:0763-E-AB-34268-01Size:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTA2 (Actin, Alpha 2, Smooth Muscle, Aorta) is a Protein Coding gene. Diseases associated with ACTA2 include Multisystemic Smooth Muscle Dysfunction Syndrome and Moyamoya Disease 5. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. GO annotations related to this gene include protein kinase binding. An important paralog of this gene is ACTG2. ACTA1 (Actin, Alpha 1, Skeletal Muscle) is a Protein Coding gene. Diseases associated with ACTA1 include Nemaline Myopathy 3, Autosomal Dominant Or Recessive and Myopathy, Congenital, With Fiber-Type Disproportion. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. GO annotations related to this gene include structural constituent of cytoskeleton and myosin binding. An important paralog of this gene is ACTC1. ACTG2 (Actin, Gamma 2, Smooth Muscle, Enteric) is a Protein Coding gene. Diseases associated with ACTG2 include Visceral Myopathy and Chronic Intestinal Pseudoobstruction. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and GPCR Pathway. An important paralog of this gene is ACTA2.
Abbreviation
Α-SMA
UniProt
P62736, P68133, P63267
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from α-SMA
Target
A actin; AAT6; ACTA; ACTA2; Actin alpha 2 smooth muscle aorta; Actin aortic smooth muscle; Actin; aortic smooth muscle; ACTSA; ACTVS; Alpha 2 actin; Alpha actin 2; Alpha cardiac actin; alpha sma; Alpha-actin-2; Cell growth inhibiting gene 46 protein; Cell growth-inhibiting gene 46 protein; GIG46; Growth inhibiting gene 46; MYMY5; ACTC; ACTC; ACTC1; Actin alpha cardiac muscle 1; Actin; alpha cardiac muscle 1; Alpha-cardiac actin; ASD5; CMD1R; CMH11; LVNC4; a actin; Actin alpha skeletal muscle; Actin; actin; alpha 1; skeletal muscle 1; actin; alpha 1; skeletal muscle; Actin; alpha skeletal muscle; actina; actine; ACTS; aktin; Alpha Actin 1; ; ASMA; CFTD; CFTD1; CFTDM; MPFD; NEM1; NEM2; NEM3; nemaline myopathy type 3
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC-p; IF
Field of Research
Cancer; Cardiovascular; Developmental Biology; Signal Transduction; Stem Cells
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
WB 1:500-2000; IHC 1:50-300; IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
42kDa
Observed Molecular Weight
42kDa
Citation 01
https://www.nature.com/articles/s41467-022-30464-8
Citation 02
https://www.sciencedirect.com/science/article/pii/S0141813022026228
Citation 03
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068511/
Citation 04
https://www.sciencedirect.com/science/article/pii/S002432052200577X
Citation 05
https://www.sciencedirect.com/science/article/pii/S0024320522009560
Citation 06
https://www.mdpi.com/2150366
Citation 07
https://www.mdpi.com/2073-4409/8/11/1435
Citation 08
https://onlinelibrary.wiley.com/doi/abs/10.1002/cam4.5081
Citation 09
https://www.mdpi.com/1587758
Citation 10
https://www.sciencedirect.com/science/article/pii/S0022030223000644
Citation 11
https://www.tandfonline.com/doi/abs/10.1080/21655979.2021.1954580
Citation 12
https://jpet.aspetjournals.org/content/364/3/399.abstract
Isotype
IgG