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EBF2 Polyclonal Antibody

CAT: 0763-E-AB-19794-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-19794-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
Abbreviation
EBF2
UniProt
Q9HAK2
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human EBF2
Target
COE 2; COE2; COE2; Collier Olf and EBF 2; Early B cell factor 2; Early B-cell factor 2; EBF 2; EBF-2; Ebf2; FLJ11500; Metencephalon mesencephalnon olfactory transcription factor 1; O/E 3; O/E3; OE 3; OE3; OLF 1/EBF like 3; Transcription factor COE2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Epigenetics and Nuclear Signaling; Neuroscience
Purification
Antigen affinity purification
Concentration
1.68 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
63 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

UniProtKB · Q9HAK2

Transcription factor COE2

COE2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9HAK2
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EBF2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A0PJM4, A6NMF7, F5H645, Q66VZ3, Q6DK36, Q6IS86, Q6ISA4
Protein keywords

Molecular function

ActivatorDevelopmental proteinDNA-binding

Coding sequence diversity

Alternative splicing

Ligand

Metal-bindingZinc

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

Biological process

TranscriptionTranscription regulation

Domain

Zinc-finger

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