ECH1 Polyclonal Antibody

• Background :

  This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.

• Abbreviation :

  ECH1

• UniProt :

  Q13011

• Host :

  Rabbit

• Reactivity :

  Human; Rat

• Immunogen :

  Fusion protein of human ECH1

• Target :

  4) -dienoyl-CoA isomerase;5) -Delta (2; Delta (3 5) Delta (2 4) dienoyl CoA isomerase; Delta (3 5) Delta (2 4) dienoyl CoA isomerase mitochondrial; Delta (3; Delta3 5 delta2 4 dienoyl CoA isomerase; Dienoyl CoA isomerase; ECH 1; Ech1; ECH1; Enoyl Coenzyme A hydratase 1; Enoyl Coenzyme A hydratase 1 peroxisomal; HPXEL; mitochondrial; MS1034; Peroxisomal enoyl CoA hydratase 1; Peroxisomal enoyl coenzyme A hydratase like protein

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB; IHC

• Field of Research :

  Cancer; Cardiovascular; Metabolism; Signal transduction; Tags and Cell markers

• Purification :

  Antigen affinity purification

• Concentration :

  0.6 mg/mL

• Dilution :

  WB 1:500-1:2000; IHC 1:50-1:300

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  36 kDa

• Observed Molecular Weight :

  Refer to figures

• Isotype :

  IgG