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HIST1H2BK Polyclonal Antibody

CAT: 0763-E-AB-18892-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-18892-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family. The protein encoded is an antimicrobial protein with antibacterial and antifungal activity. Two transcripts that encode the same protein have been identified for this gene, which is found in the histone microcluster on chromosome 6p21.33.
Abbreviation
HIST1H2BK
UniProt
O60814
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human HIST1H2BK
Target
H2B histone family member T ; H2B K; H2B/S ; H2BFAiii ; H2BFT; HIRA-interacting protein 1 ; HIRIP1; HIST1H2BK; Histone family member; Histone H2B type 1-K
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Epigenetics and Nuclear Signaling
Purification
Antigen affinity purification
Concentration
0.72 mg/mL
Dilution
IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · O60814

Histone H2B type 1-K

H2B1K_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O60814
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
H2BC12
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
H2B K
EC number
—
Processing
—
Secondary accessions
A8K7P7, Q2VPI7
Protein keywords

Technical term

3D-structureDirect protein sequencingReference proteome

PTM

AcetylationADP-ribosylationGlycoproteinHydroxylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Molecular function

AntibioticAntimicrobialDNA-binding

Cellular component

ChromosomeNucleosome coreNucleus

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