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HIST1H2AH Polyclonal Antibody

CAT: 0763-E-AB-15092-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-15092-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33.
Abbreviation
HIST1H2AH
UniProt
Q96KK5
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human HIST1H2AH
Target
H2AH; H2A/S; H2AFALii; dJ86C11.1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Cancer; Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
14kDa
Isotype
IgG

UniProtKB · Q96KK5

Histone H2A type 1-H

H2A1H_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96KK5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
H2AC12
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Technical term

3D-structureReference proteome

PTM

AcetylationCitrullinationHydroxylationIsopeptide bondMethylationPhosphoproteinUbl conjugation

Cellular component

ChromosomeNucleosome coreNucleus

Molecular function

DNA-binding

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