GCAT Polyclonal Antibody

• Background :

  The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14.

• Abbreviation :

  GCAT

• UniProt :

  O75600

• Host :

  Rabbit

• Reactivity :

  Human; Mouse

• Immunogen :

  Fusion protein of human GCAT

• Target :

  2 amino 3 ketobutyrate CoA ligase ;2 amino 3 ketobutyrate coenzyme A ligase; mitochondrial;2-amino-3-ketobutyrate coenzyme A ligase; AKB ligase; Aminoacetone synthase; GCAT; Glycine acetyltransferase; glycine C acetyltransferase ; glycine C acetyltransferase (2 amino 3 ketobutyrate coenzyme A ligase) ; KBL; KLB; mitochondrial

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB

• Field of Research :

  Cancer; Metabolism; Signal transduction

• Purification :

  Antigen affinity purification

• Concentration :

  1.02 mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  45 kDa

• Observed Molecular Weight :

  Refer to figures

• Isotype :

  IgG