MDFI Polyclonal Antibody

• Background:

  This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.MDFI (MyoD Family Inhibitor) is a Protein Coding gene. GO annotations related to this gene include transcription factor binding. An important paralog of this gene is MDFIC.

• Abbreviation:

  MDFI

• UniProt:

  Q99750

• Host:

  Rabbit

• Reactivity:

  Human; Rat

• Immunogen:

  Fusion protein of human MDFI

• Target:

  I MF; I mfa; Inhibitor of MyoD family a; Mdfi; MDFI; MyoD family inhibitor; Myogenic repressor I-mf; OTTHUMP00000016375; OTTHUMP00000016376; OTTHUMP00000196103; OTTHUMP00000196414; OTTHUMP00000196415

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Epigenetics and Nuclear Signaling; Developmental Biology

• Purification:

  Antigen affinity purification

• Concentration:

  0.96 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:50-1:300

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  25 kDa

• Observed Molecular Weight:

  Refer to figures

• Isotype:

  IgG