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WDFY2 Polyclonal Antibody

CAT: 0763-E-AB-18486-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-18486-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
WD repeat and FYVE domain-containing protein 2 (WDFY2), also known as WDF2 and ZFYVE22, is a 400 amino acid protein that localizes to a set of small endosomes that are found within 100 nm from the plasma membrane. Highly conserved between species, WDFY2 consists of one FYVE-type zinc finger and seven WD repeats. The FYVE domain is a cysteine-rich domain of about 70 amino acids. Its primary role is to target signal-transducing proteins to cell membranes through binding to the membrane lipid phosphatidylinositol-3-phosphate with high specificity. WD-repeats are generally found in clusters of seven. They have no intrinsic catalytic activity, but they serve as a platform for protein-protein interactions. WDFY2 is suspected to play a critical role in the endocytic pathway.
Abbreviation
WDFY2
UniProt
Q96P53
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human WDFY2
Target
PROF; Propeller-FYVE protein; RP11 147H23.1; WD repeat and FYVE domain containing 2; WD repeat and FYVE domain-containing protein 2; WD40 and FYVE domain containing 2; WD40- and FYVE domain-containing protein 2; WDF2; Wdfy2; WDFY2; ZFYVE22; Zinc finger FYVE domain-containing protein 22
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IHC
Field of Research
Signal transduction
Purification
Antigen affinity purification
Concentration
0.6 mg/mL
Dilution
WB 1:500-1:2000; IHC 1:30-1:150
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
45 kDa
Observed Molecular Weight
Refer to figures
Isotype
IgG

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