WDFY2 Polyclonal Antibody

• Background :

  WD repeat and FYVE domain-containing protein 2 (WDFY2), also known as WDF2 and ZFYVE22, is a 400 amino acid protein that localizes to a set of small endosomes that are found within 100 nm from the plasma membrane. Highly conserved between species, WDFY2 consists of one FYVE-type zinc finger and seven WD repeats. The FYVE domain is a cysteine-rich domain of about 70 amino acids. Its primary role is to target signal-transducing proteins to cell membranes through binding to the membrane lipid phosphatidylinositol-3-phosphate with high specificity. WD-repeats are generally found in clusters of seven. They have no intrinsic catalytic activity, but they serve as a platform for protein-protein interactions. WDFY2 is suspected to play a critical role in the endocytic pathway.

• Abbreviation :

  WDFY2

• UniProt :

  Q96P53

• Host :

  Rabbit

• Reactivity :

  Human; Mouse

• Immunogen :

  Fusion protein of human WDFY2

• Target :

  PROF; Propeller-FYVE protein; RP11 147H23.1; WD repeat and FYVE domain containing 2; WD repeat and FYVE domain-containing protein 2; WD40 and FYVE domain containing 2; WD40- and FYVE domain-containing protein 2; WDF2; Wdfy2; WDFY2; ZFYVE22; Zinc finger FYVE domain-containing protein 22

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  WB; IHC

• Field of Research :

  Signal transduction

• Purification :

  Antigen affinity purification

• Concentration :

  0.6 mg/mL

• Dilution :

  WB 1:500-1:2000; IHC 1:30-1:150

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  45 kDa

• Observed Molecular Weight :

  Refer to figures

• Isotype :

  IgG