MAPK8IP3 Polyclonal Antibody

CAT: 0763-E-AB-18142-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0763-E-AB-18142-01Size:20 µL
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Background
The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. MAPK8IP3 (Mitogen-Activated Protein Kinase 8 Interacting Protein 3) is a Protein Coding gene. Among its related pathways are MAPK signaling pathway and Arf6 trafficking events. GO annotations related to this gene include kinesin binding and receptor signaling complex scaffold activity. An important paralog of this gene is SPAG9.
Abbreviation
MAPK8IP3
UniProt
Q9UPT6
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human MAPK8IP3
Target
C-jun-amino-terminal kinase-interacting protein 3; FLJ00027; Homolog of Drosophila Sunday driver 2; JIP-3; JIP3; JIP3; JNK / Stress Activated Protein Kinase Associated Protein 1; JNK Interacting Protein 3; JNK MAP kinase scaffold protein 3; JNK-interacting protein 3; JNK/SAPK associated protein 1; JSAP1; KIAA1066; MAPK8IP3; Mitogen Activated Protein kinase 8 Interacting Protein 3; Mitogen-activated protein kinase 8-interacting protein 3; Syd; SYD2
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Signal Transduction
Purification
Antigen affinity purification
Concentration
1.26 mg/mL
Dilution
IHC 1:40-1:200
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

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