UCN3 Polyclonal Antibody

• Background :

  This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family of proteins. The encoded preproprotein is proteolytically processed to generate the mature peptide hormone, which is secreted by pancreatic beta and alpha cells. This hormone is an endogenous ligand for corticotropin-releasing factor receptor 2 and may regulate insulin secretion in response to plasma glucose levels. Patients with type 2 diabetes exhibit reduced levels of the encoded protein in beta cells. In the brain, the encoded protein may be responsible for the effects of stress on appetite.

• Abbreviation :

  UCN3

• UniProt :

  Q969E3

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Synthetic peptide of human UCN3

• Target :

  MGC119002; OTTHUMP00000018999 ; Prepro urocortin 3; SCP; SPC; Stresscopin ; Ucn III ; UCN3 ; UCN3 urocortin 3 stresscopin; UCNIII; Urocortin 3; Urocortin 3 stresscopin; Urocortin III

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  IHC

• Field of Research :

  Cancer; Cardiovascular; Metabolism; Neuroscience; Signal transduction

• Purification :

  Antigen affinity purification

• Concentration :

  1.4 mg/mL

• Dilution :

  IHC 1:50-1:300

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype :

  IgG