REST Polyclonal Antibody

• Background:

  This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described.

• Abbreviation:

  REST

• UniProt:

  Q13127

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Synthetic peptide of human REST

• Target:

  Neural Restrictive Silencer Factor; Neural-restrictive silencer factor; Neuron Restrictive Silencer Factor; NRSF; RE1 silencing transcription factor; RE1-silencing transcription factor; Repressor binding to the X2 box; rest; REST protein; REST; X2 box repressor; XBR

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Cancer; Epigenetics and Nuclear Signaling; Neuroscience

• Purification:

  Antigen affinity purification

• Concentration:

  1 mg/mL

• Dilution:

  IHC 1:30-1:150

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG