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TRPC4AP Polyclonal Antibody

CAT: 0763-E-AB-17161-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-17161-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TRPC4AP (transient receptor potential cation channel, subfamily C, member 4 associated protein), also known as TRUSS or TRRP4AP, is a 797 amino acid protein that is expressed in a variety of tissues, with highest expression in liver, heart, testis and brain. Thought to function as a scaffolding protein, TRPC4AP interacts with TNF-R1 and may both link TNF-R1 to the IKK signalsome complex, and participate in the activation of NFκB p50, an event that occurs in response to TNF-R1 ligation. TRPC4AP exists as multiple alternatively spliced isoforms that are encoded by a gene whicHuman, Mouseaps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome.
Abbreviation
TRPC4AP
UniProt
Q8TEL6
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Fusion protein of human TRPC4AP
Target
C20orf188; TRPC4AP; Chromosome 20 open reading frame 188; Protein TAP1; Protein TRUSS; Short transient receptor potential channel 4 associated protein; Short transient receptor potential channel 4-associated protein; TAP1 protein; TNF receptor ubiquitous scaffolding/signaling protein; TNF-receptor ubiquitous scaffolding/signaling protein; TP4AP; Transient receptor potential cation channel; subfamily C; member 4 associated protein; Trp4 associated protein; Trp4-associated protein; Trpc4 associated protein; Trpc4-associated protein; TRPC4AP; TRRP4AP; TRUSS; Tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Epigenetics and Nuclear Signaling; Signal transduction
Purification
Affinity purification
Concentration
0.9 mg/mL
Dilution
IHC 1:30-150
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG