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DEAF1 Polyclonal Antibody

CAT: 0763-E-AB-16381-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-16381-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Suppressin, also known as DEAF1 (deformed epidermal autoregulatory factor 1), SPN, NUDR (nuclear DEAF-1-related transcriptional regulator), or ZMYND5 (zinc finger MYND domain-containing protein 5), is a transcription factor required for embryonic development. Suppressin contains one SAND domain and one C-terminal MYND-type zinc finger. It interacts with LMO4 and CLIM-2, suggesting that it plays a role mediating cell fate and embryonic pattern formation. Suppressin is expressed in a variety of tissues and localizes to the nucleus. Several isoforms exist due to alternative splicing and, depending on the isoform, Suppressin is secreted in some cell types. Secreted Suppressin can function to inhibit cell proliferation, arresting cells in the G0 or G1 phase. Mutations in the gene encoding Suppressin may result in a growth advantage leading to the development and progression of neoplasia. This suggest that Supressin is a potential target for cancer therapy.
Abbreviation
DEAF1
UniProt
O75398
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human DEAF1
Target
Deaf1; DEAF1 transcription factor; DEAF1; Deformed epidermal autoregulatory factor 1 homolog; Nuclear DEA1 related transcriptional regulator; Nuclear DEAF-1-related transcriptional regulator; NUDR; SPN; Suppressin; Zinc finger MYND domain containing protein 5; Zinc finger MYND domain-containing protein 5; ZMYND5
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cell biology; Epigenetics and Nuclear Signaling
Purification
Affinity purification
Concentration
1.4 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

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Alternative Products

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MBS2521045-01DEAF1 Polyclonal Antibody
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