LIN28B Polyclonal Antibody

• Background:

  The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]

• Abbreviation:

  LIN28B

• UniProt:

  Q6ZN17

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Synthetic peptide of human LIN28B

• Target:

  CSDD 2; CSDD2; FLJ16517; Lin 28 homolog B (C. elegans) ; Lin 28.2; Lin-28B; LIN28B; LN28B; Protein lin-28 homolog B

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Cancer; Epigenetics and Nuclear Signaling

• Purification:

  Affinity purification

• Concentration:

  0.3 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  27kDa

• Isotype:

  IgG