PTPRM Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, whicHuman, Mouseay be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.

• Abbreviation:

  PTPRM

• UniProt:

  P28827

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthetic peptide of human PTPRM

• Target:

  HR PTPu; Protein tyrosine phosphatase mu; Protein tyrosine phosphatase receptor type M; Protein tyrosine phosphatase receptor type mu polypeptide; Protein-tyrosine phosphatase mu; PTPRL1; Ptprm; PTPRM; R PTP mu; R-PTP-mu; Receptor type tyrosine protein phosphatase mu; Receptor-type tyrosine-protein phosphatase mu; RPTPM; RPTPU

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Concentration:

  1.1 mg/mL

• Dilution:

  IHC 1:100-1:300

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG