PTPRM Polyclonal Antibody

CAT: 0866-RD78745A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD78745A-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, whicHuman, Mouseay be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.
Description
This is a PTPRM Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
HR PTPu, Protein tyrosine phosphatase mu, Protein tyrosine phosphatase receptor type M, Protein tyrosine phosphatase receptor type mu polypeptide, Protein-tyrosine phosphatase mu, PTPRL1, Ptprm, PTPRM, R PTP mu, R-PTP-mu, Receptor type tyrosine protein phosphatase
Swiss Prot
P28827
Accession Number
NP_002836
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human PTPRM
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1.1 mg/mL
Dilution
IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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