PTPRM Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, whicHuman, Mouseay be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.

• Description:

  This is a PTPRM Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  HR PTPu, Protein tyrosine phosphatase mu, Protein tyrosine phosphatase receptor type M, Protein tyrosine phosphatase receptor type mu polypeptide, Protein-tyrosine phosphatase mu, PTPRL1, Ptprm, PTPRM, R PTP mu, R-PTP-mu, Receptor type tyrosine protein phosphatase

• Swiss Prot:

  P28827

• Accession Number:

  NP_002836

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide of human PTPRM

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1.1 mg/mL

• Dilution:

  IHC 1:100-1:300

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG