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FAM3B Polyclonal Antibody

CAT: 0763-E-AB-15013-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-15013-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events. The gene encoding FAM3B maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome.
Abbreviation
FAM3B
UniProt
P58499
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Recombinant protein of human FAM3B
Target
2-21; C21orf11; C21orf76; Cytokine like protein 2 21; Cytokine-like protein 2-21; Fam3b; FAM3B; Family with sequence similarity 3 member B; ORF9; Pancreatic-derived factor; PANDER; PRED44; Protein FAM3B
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Metabolism; Immunology
Purification
Affinity purification
Concentration
0.5 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · P58499

Protein FAM3B

FAM3B_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P58499
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FAM3B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
—
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

Apoptosis

Molecular function

Cytokine

Technical term

Direct protein sequencingProteomics identificationReference proteome

PTM

Disulfide bondGlycoprotein

Ligand

Lectin

Cellular component

Secreted

Domain

Signal

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