ECE2 Polyclonal Antibody

• Background :

  Endothelin-converting enzymes, such as ECE2 (EC 3.4.24.71), are type II metalloproteases that generate functionally pleiotropic members of the endothelin vasoactive peptide family. It converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.

• Abbreviation :

  ECE2

• UniProt :

  O60344

• Host :

  Rabbit

• Reactivity :

  Human; Mouse

• Immunogen :

  Recombinant protein of human ECE2

• Target :

  ECE 2; ECE-2; ECE2; ECE2; Endothelin converting enzyme 2; Endothelin-converting enzyme 2 region; Hypothetical protein MGC2408; KIAA0604; MGC17664; MGC78487

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Applications :

  IHC

• Field of Research :

  Cardiovascular; Neuroscience; Signal Transduction

• Purification :

  Affinity purification

• Concentration :

  0.1 mg/mL

• Dilution :

  IHC 1:50-1:200

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions :

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype :

  IgG