ECE2 Polyclonal Antibody

• Background:

  Endothelin-converting enzymes, such as ECE2 (EC 3.4.24.71), are type II metalloproteases that generate functionally pleiotropic members of the endothelin vasoactive peptide family. It converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.

• Abbreviation:

  ECE2

• UniProt:

  O60344

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Recombinant protein of human ECE2

• Target:

  ECE 2; ECE-2; ECE2; ECE2; Endothelin converting enzyme 2; Endothelin-converting enzyme 2 region; Hypothetical protein MGC2408; KIAA0604; MGC17664; MGC78487

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Cardiovascular; Neuroscience; Signal Transduction

• Purification:

  Affinity purification

• Concentration:

  0.1 mg/mL

• Dilution:

  IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG