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MARK4 Polyclonal Antibody

CAT: 0763-E-AB-13402-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-13402-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Abbreviation
MARK4
UniProt
Q96L34
Host
Rabbit
Reactivity
Human; Mouse
Immunogen
Synthetic peptide of human MARK4
Target
FLJ90097; KIAA1860; MAP / microtubule affinity regulating kinase 4; MAP / microtubule affinity regulating kinase 4L; MAP/microtubule affinity regulating kinase 4; MAP/microtubule affinity regulating kinase like 1; MAP/microtubule affinity-regulating kinase 4; MAP/microtubule affinity-regulating kinase-like 1; MARK 4; MARK 4L; MARK L1; MARK4; MARK4 serine / threonine protein kinase; MARK4 serine/threonine protein kinase; MARK4; MARK4S; MARKL 1; MARKL1; Nbla00650; Putative protein product of Nbla00650
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Signal Transduction
Purification
Affinity purification
Concentration
1 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q96L34

MAP/microtubule affinity-regulating kinase 4

MARK4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96L34
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MARK4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.1
Processing
—
Secondary accessions
Q8NG37, Q96JG7, Q96SQ2, Q9BYD8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Biological process

Cell cycleCell divisionCilium biogenesis/degradationMitosis

Cellular component

Cell projectionCytoplasmCytoskeleton

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

PTM

PhosphoproteinUbl conjugation

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