DAAM1 Polyclonal Antibody

• Background:

  Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton and several formin homology (FH) proteins have been associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The protein encoded by this gene is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl) -Rho complex.

• Abbreviation:

  DAAM1

• UniProt:

  Q9Y4D1

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthetic peptide of human DAAM1

• Target:

  DAAM 1; Dishevelled associated activator of morphogenesis 1; FLJ41657; KIAA0666

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Signal Transduction; Stem Cells

• Purification:

  Affinity purification

• Concentration:

  1.2 mg/mL

• Dilution:

  WB 1:200-1:1000; IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  123kDa

• Citation 01:

  https://www.mdpi.com/1422-0067/23/9/5128

• Isotype:

  IgG