APBA2 Polyclonal Antibody

CAT: 0763-E-AB-12975-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0763-E-AB-12975-01Size:20 µL
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AVAILABILITY: InStock
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Background
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP) . It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.
Abbreviation
APBA2
UniProt
Q99767
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide of human APBA2
Target
Adapter protein X11beta; Amyloid beta A4 precursor protein-binding family A member 2; APBA2; APBA2; D15S1518E; HsT16821; LIN 10; MGC:14091; MGC99508; Mint 2; Mint-2; MINT2; Neuron-specific X11L protein; Neuronal Munc18-1-interacting protein 2; Phosphotyrosine binding/interacting domain (PTB) bearing protein; X11 beta; X11 like protein; X11l
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Neuroscience
Purification
Affinity purification
Concentration
0.6 mg/mL
Dilution
IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

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