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GUCY1A3 Polyclonal Antibody

CAT: 0763-E-AB-10898-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-10898-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.
Abbreviation
GUCY1A3
UniProt
Q02108
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human GUCY1A3
Target
GC S alpha 1; GC SA3; GCS alpha 1; GCS alpha 3; GCS-alpha-1; GCS-alpha-3; GCYA3; Guanylate cyclase 1 soluble alpha 3; Guanylate cyclase soluble subunit alpha 1; Guanylate cyclase soluble subunit alpha 3; Guanylate cyclase soluble subunit alpha-3; Guanylate cyclase; nitric oxide-sensitive; alpha-1 subunit; Guc1a1; GUC1A3; GUCA3; GUCSA3; Gucy1a1; Gucy1a3; MYMY6; nitric oxide-sensitive Guanylate cyclase; alpha-1 subunit; NOGC; alpha-1 subunit; Soluble guanylate cyclase large subunit
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular; Signal Transduction
Purification
Affinity purification
Concentration
0.2 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · Q02108

Guanylate cyclase soluble subunit alpha-1

GCYA1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q02108
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GUCY1A1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
GCS-alpha-1
EC number
4.6.1.2
Processing
—
Secondary accessions
D3DP19, D6RDW3, O43843, Q8TAH3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

cGMP biosynthesis

Cellular component

Cytoplasm

Ligand

GTP-bindingNucleotide-binding

Molecular function

Lyase

PTM

Phosphoprotein

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