APLF Polyclonal Antibody

• Background:

  C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks. Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly (ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro.

• Abbreviation:

  APLF

• UniProt:

  Q8IW19

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant protein of human APLF

• Target:

  2010301N04Rik; AI452191; Aplf; APLF; Aprataxin and PNK-like factor; Apurinic-apyrimidinic endonuclease APLF; C2orf13; PNK and APTX like FHA protein; PNK and APTX-like FHA domain-containing protein; RGD1565557; XIP1; XRCC1 interacting protein 1; XRCC1-interacting protein 1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  IHC

• Field of Research:

  Epigenetics and Nuclear Signaling

• Purification:

  Affinity purification

• Concentration:

  0.5 mg/mL

• Dilution:

  IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Isotype:

  IgG