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TGFA Polyclonal Antibody

CAT: 0763-E-AB-10642-02Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-10642-02Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. This protein may act as either a transmembrane-bound ligand or a soluble ligand. This gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Abbreviation
TGFA
UniProt
P01135
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
Recombinant protein of human TGFA
Target
EGF like TGF; EGF-like TGF; ETGF; TFGA; TGF A; TGF type 1; TGF-alpha; Tgfa; TGFA; Transforming growth factor alpha; Transforming growth factor alpha precursor; Wa1; Waved 1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
IHC
Field of Research
Cancer; Cardiovascular; Signal Transduction
Purification
Affinity purification
Concentration
0.4 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype
IgG

UniProtKB · P01135

Protransforming growth factor alpha

TGFA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01135
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TGFA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A8K286, Q15577, Q53SK7, Q9BS56, Q9UEI3, Q9UKM1, Q9UKM2, Q9UKM3
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell membraneMembraneSecreted

PTM

Disulfide bondGlycoproteinLipoproteinPalmitate

Domain

EGF-like domainSignalTransmembraneTransmembrane helix

Molecular function

Growth factorMitogen

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