Products for Research Use Only
RegisterLogin

TGF beta 1 Polyclonal Antibody

CAT: 0763-E-AB-93274-01Size: 60 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0763-E-AB-93274-01Size:60 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
Abbreviation
TGF beta 1
UniProt
P01137
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide of human TGF beta 1
Target
TGFB1; CED; DPD1; LAP; TGFB; TGFbeta; TGF-β
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Cancer; Cardiovascular; Metabolism; Signal Transduction; Stem Cells
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
44kDa
Observed Molecular Weight
12KDa/25KDa/45-60KDa
Isotype
IgG

UniProtKB · P01137

Transforming growth factor beta-1 proprotein

TGFB1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01137
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
TGFB1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A8K792, Q9UCG4
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoprotein

Disease

Disease variant

Cellular component

Extracellular matrixSecreted

Molecular function

Growth factorMitogen

Domain

Signal
Product Datasheet
Loading...

Related Products

CatalogName
E-AB-40637-01TGF beta 2 Polyclonal Antibody
AN301902L-01Recombinant TGF beta 1 Monoclonal Antibody
E-AB-81441-01Recombinant TGF beta 1 Monoclonal Antibody
E-AB-93192-01TGF beta Receptor I (TGFBR1) Polyclonal Antibody
PKSR030419-01Recombinant Rat TGFB1/TGF-beta 1 Protein
PKSH032007-01Recombinant Human TGFB1/TGF-beta 1 Protein
E-EL-0162-01TGF-β1 (Transforming Growth Factor Beta 1) ELISA Kit
ELAB6100-MTGF-β1 Monoclonal Antibody
PKSM041497-01Recombinant Mouse TGF beta 1 protein (His Tag)
PKSH034147-01Recombinant Human TGF beta 1 protein (His Tag)

Alternative Products

CatalogName
JOT-AP06254-01Amyloid-beta Polyclonal Antibody
JOT-AP09791-01Beta-Catenin Polyclonal Antibody
JOT-AP00213-01Actin Beta Polyclonal Antibody
JOT-AP07024-01PDGFR-Beta Polyclonal Antibody
JOT-AP07235-01PKI Beta Polyclonal Antibody
JOT-AP04542-01Inhibin Beta-A Polyclonal Antibody
MBS2538000-01TCR beta Polyclonal Antibody
MBS8593180-01GMF-beta Polyclonal Antibody
MBS8522901-01Glucuronidase beta Polyclonal Antibody
MBS8526656-01Galactosidase beta Polyclonal Antibody

Popular Products