DHODH-IN-1

DHODH-IN-1

• CAS Number: 1800296-63-2
• UNSPSC Description: DHODH-IN-1 (compound 18d) is a potent Dihydroorotate Dehydrogenase (DHODH) inhibitor with an IC50 of 25 nM. DHODH-IN-1 is an inhibitor of pyrimidine biosynthesis pathway[1].
• Target Antigen: Dihydroorotate Dehydrogenase; DNA/RNA Synthesis
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/dhodh-in-1.html
• Smiles: FC1=CC(C2CC2)=CN=C1N3N=C(OC(C)C)C(OC4=C(F)C=CC=C4F)=C3C
• Molecular Weight: 403.40
• References & Citations: [1]Lucas-Hourani M, et al.Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH).J Med Chem. 2015 Jul 23;58(14):5579-98.
• Shipping Conditions: Room Temperature