DHODH-IN-16

• UNSPSC Description:

  DHODH-IN-16 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.396 nM for human DHODH[1].

• Target Antigen:

  Dihydroorotate Dehydrogenase; DNA/RNA Synthesis

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dhodh-in-16.html

• Smiles:

  O=C1C2=C(C(C(C)C)=CN1C3=C(C)C=CC=C3)C=C(N4N=C(CO)N(CC)C4=O)C(F)=C2

• Molecular Weight:

  436.48

• References & Citations:

  [1]Scott Kuduk, et al. Dihydroorotate dehydrogenase inhibitors. WO2020212897A1.

• Shipping Conditions:

  Room Temperature

• CAS Number:

  2511248-11-4