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OST48 rabbit pAb

CAT: 0855-ES14360-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES14360-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008]
Description
This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq, Jul 2008],
UniProt
P39656
Swiss Prot
P39656
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human OST48 AA range: 54-104
Target
OST48
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Single-pass type I membrane protein .
Gene ID (Human)
1650

UniProtKB · P39656

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

OST48_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P39656
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
DDOST
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
DDOST 48 kDa subunit, Oligosaccharyl transferase 48 kDa subunit
EC number
—
Processing
Precursor
Secondary accessions
B2RDQ4, B4DJE3, B4DLI2, O43244, Q5VWA5, Q8NI93, Q9BUI2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

Congenital disorder of glycosylationDisease variant

Cellular component

Endoplasmic reticulumMembrane

Domain

SignalTransmembraneTransmembrane helix

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