Products for Research Use Only
RegisterLogin

RecombinantFGF-6, Human

CAT: 0013-GTR18991702-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18991702-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Fibroblast Growth Factor-6 (FGF-6) is a cytokine belonging to the heparin-binding FGF family, and is structurally related to other members of FGF family, particularly FGF-4. In vivo, FGF-6 exhibits an expression profile predominantly restricted tothe myogenic lineage, and it preferentially binds to two of the FGF receptors: FGFR1 and FGFR4. FGF-6 functions in muscle regeneration, myoblast proliferation and migration, and muscle differentiation in a dose-dependent manner. In vivo high concentration of recombinant FGF-6 up-regulates and down-regulates FGFR1 and FGFR4, respectively, as FGFR1 promotes the proliferation while FGFR4 promotes the differentiation in the muscle. Besides its dual function in muscle regeneration, FGF-6 may act as a regulator of bone metabolism as well.Recombinant human Fibroblast Growth Factor-6 (rhFGF-6) produced in E.coli is a single non-glycosylated polypeptide chain containing 169 amino acids. A fully biologically active molecule, rhFGF-6 has a molecular mass of 18.8 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
Product Name Alternative
FGF6; Fibroblast Growth Factor-6, HBGF-6, HST-2
Source
Escherichia coli.
Endotoxin
< 0.2 EU/μg, determined by LAL method.
Purity
> 95% as analyzed by SDS-PAGE and HPLC.
Bioactivity
ED50 4x 10ˆ5 units/mg.
Form
Lyophilized after extensive dialysis against PBS.
Molecular Weight
18.8 kDa, observed by reducing SDS-PAGE.
Storage Conditions
Lyophilized recombinant human Fibroblast Growth Factor-6 (rhFGF-6) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhFGF-6 remains stable up to 2 weeks at 4°C or up to 3 months at -20°C.
Notes
For research use only.
Applications Notes
Reconstituted in ddH2O at 100 μg/mL.
Preservative
Lyophilized after extensive dialysis against PBS.
AA Sequence
MGTRANNTL LDSRGWGTLL SRSRAGLAGE IAGVNWESGY LVGIKRQRRL YCNVGIGFHL QVLPDGRISG THEENPYSLL EISTVERGVV SLFGVRSALF VAMNSKGRLY ATPSFQEECK FRETLLPNNY NAYESDLYQG TYIALSKYGR VKRGSKVSPI MTVTHFLPRI

Related Products

CatalogName
GTR18991780-01RecombinantFGF-12, Human
GTR18991658-01RecombinantFGF-8e, Human
GTR18991635-01RecombinantFGF-9, Human
GTR18990433-01RecombinantFGF-16, Human
GTR18991802-01RecombinantFGF-10, Human
GTR18991735-01RecombinantFGF-21, Human
GTR18991713-01RecombinantFGF-4, Human
GTR18991769-01RecombinantFGF-18, Human
GTR18991691-01RecombinantFGF-8, Human
GTR18991680-01RecombinantFGF-8a, Human

Alternative Products

CatalogName
BK0043-01RecombinantFGF-6, Human
BK0043RecombinantFGF-6,Human
BK0040RecombinantFGF-21,Human
BK0047RecombinantFGF-8e,Human
BK0199-01RecombinantFGF-16, Human
BK0047-01RecombinantFGF-8e, Human
BK0199RecombinantFGF-16,Human
BK0049RecombinantFGF-9,Human
BK0045RecombinantFGF-8a,Human
BK0042RecombinantFGF-4,Human

Popular Products