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NLRP3-IN-36

CAT: 0804-HY-163494Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163494Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NLRP3-IN-36 (Compound 111) is an NLRP3 inhibitor (IC50 [1].
UNSPSC
12352005
Target
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nlrp3-in-36.html
Solubility
10 mM in DMSO
Smiles
O=C(N(CC1=CC(O)=CC2=C1NN=C2)C)C(C=C3OC4CC4)=CC(F)=C3C5=CC(C#N)=CC=C5
Molecular Formula
C26H21FN4O3
Molecular Weight
456.47
References & Citations
[1]Hartman, G. Preparation of indazole and pyrazolopyridine compounds as inhibitors of NLRP3 inflammasome. World Intellectual Property Organization, WO2024064655 A1 2024-03-28
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NLRP3

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