Anti-AP-3 complex subunit beta-1 AP3B1 Antibody

• Description:

  Boster Bio Anti-AP-3 complex subunit beta-1 AP3B1 Antibody catalog # A04904. Tested in WB applications. This antibody reacts with Human, Mouse.

• Synonyms:

  AP-3 complex subunit beta-1; Adaptor protein complex AP-3 subunit beta-1; Adaptor-related protein complex 3 subunit beta-1; Beta-3A-adaptin; Clathrin assembly protein complex 3 beta-1 large chain; AP3B1; ADTB3A;

• Gene Name:

  AP3B1

• UniProt:

  O00203

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant protein of human AP3B1.

• Clonality:

  Polyclonal

• Tissue Specificity:

  Ubiquitously expressed.

• Applications:

  WB

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Dilution:

  WB: 1:500-1:2000

• Form:

  Liquid

• Function:

  Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

• Molecular Weight:

  121320 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  AP-3 complex subunit beta-1

• Subcellular Location:

  Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Golgi apparatus . Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. .

• Protein Name:

  AP-3 complex subunit beta-1