S-Gboxin

• UNSPSC Description:

  S-Gboxin, a functional analogue of Gboxin, inhibits growth of mouse and human glioblastoma (GBM) with an IC50 of 470 nM[1]. Antitumour activity[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/S-Gboxin.html

• Purity:

  99.62

• Solubility:

  DMSO : 93.33 mg/mL (ultrasonic)|H2O : 1 mg/mL (ultrasonic;warming;heat to 67°C)

• Smiles:

  CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(CN2C(C=CC=C3)=C3[N+](C)=C2C4=CC(C(F)(F)F)=CC=C4)=O.[I-]

• Molecular Weight:

  600.45

• References & Citations:

  [1]Shi Y, et al. Gboxin is an oxidative phosphorylation inhibitor that targets glioblastoma. Nature. 2019 Mar;567(7748):341-346.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  2101317-21-7